Browsing by Subject "drug conjugates"

Now showing items 1-3 of 3

Hochtemperatur- und Mehrstufensynthesen mit miniaturisierten Durchflussreaktoren und Darstellung von Maleimid-funktionalisierten superparamagnetischen Nanopartikeln zur Anwendung in Wirkstoffkonjugaten

Hartwig, Jan (Hannover : Gottfried Wilhelm Leibniz Universität Hannover, 2016)

[no abstract]
Selective Bacterial Targeting and Infection-Triggered Release of Antibiotic Colistin Conjugates

Tegge, Werner; Guerra, Giulia; Höltke, Alexander; Schiller, Lauritz; Beutling, Ulrike; Harmrolfs, Kirsten; Gröbe, Lothar; Wullenkord, Hannah; Xu, Chunfa; Weich, Herbert; Brönstrup, Mark (Weinheim : Wiley-VCH, 2021)

In order to render potent, but toxic antibiotics more selective, we have explored a novel conjugation strategy that includes drug accumulation followed by infection-triggered release of the drug. Bacterial targeting was ...
Using iron to catch a ride - synthetic siderophores as molecular 'Trojan Horses' to visualize and treat MDR bacterial pathogens

Peukert, Carsten (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2022)

The rise in multidrug-resistant, bacterial infections, together with a shallow industrial discovery pipeline, urgently calls for novel diagnostic and therapeutic strategies. Bacterial cells, particularly Gram-negative ...

Now showing items 1-3 of 3

Browse